New study tests best order of targeted drugs for tough colorectal cancer

NCT ID NCT04787341

First seen Feb 02, 2026 · Last updated May 15, 2026 · Updated 10 times

Summary

This study is for people with advanced colorectal cancer that has not responded to standard treatments. It compares two sequences of drugs: panitumumab followed by regorafenib, or the reverse order. The goal is to see which sequence helps patients live longer and controls the cancer better. About 214 adults will take part, and all must have a specific genetic type (RAS and BRAF wild-type) and have benefited from a prior anti-EGFR treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • U.O. Oncologia 2 Universitaria

    Pisa, PI, 56126, Italy

Conditions

Explore the condition pages connected to this study.