Porphyria prevention study halted early – little data to go on

NCT ID NCT02922413

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small phase 2 trial tested whether the drug Panhematin could prevent acute attacks in people with certain types of porphyria. Only 13 participants were enrolled before the study was terminated early. Researchers tracked attacks and serious side effects, but the limited data makes it hard to draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hemin (Panhematin) given intravenously
What this could lead to
If it worked, this could point toward a way to prevent painful acute attacks in people with certain porphyrias.
What could go wrong
The trial was terminated early and only enrolled 13 people, so results are very limited. It is unclear if Panhematin is truly effective or safe for prevention.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Texas Medical Branch

    Galveston, Texas, 77555, United States

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