Scientists scan brains to see if PKU drug repairs damage

NCT ID NCT05356377

Summary

This study looked at whether Palynziq, a medication that lowers phenylalanine levels in people with PKU, leads to improvements in brain health and thinking skills. Researchers used brain scans and cognitive tests to measure changes in 6 adults with PKU who had been successfully treated with Palynziq for at least 3 months. The goal was to understand how reducing this harmful amino acid affects the brain's structure, function, and a person's ability to think clearly.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • University of Missouri

    Columbia, Missouri, 65211, United States

Conditions

Explore the condition pages connected to this study.