New drug combo aims to outsmart Treatment-Resistant head and neck cancer
NCT ID NCT04966481
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding palbociclib to cetuximab helps people with a certain genetic type of head and neck cancer live longer than cetuximab alone. Participants must have HPV-unrelated cancer with a CDKN2A gene change that has worsened after prior immunotherapy. About 81 adults will receive either the combination or single drug, and researchers will compare survival and tumor response.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Saint Luke's Hospital
WITHDRAWNKansas City, Missouri, 64111, United States
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Sanford Medical Center
RECRUITINGSioux Falls, South Dakota, 57104, United States
Contact Phone: •••-•••-••••
Contact
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Sanford Roger Maris Cancer Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Phone: •••-•••-••••
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Sanford Worthington Medical Center
NOT_YET_RECRUITINGWorthington, Minnesota, 56187, United States
Contact Phone: •••-•••-••••
Contact
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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