New study aims to cut opioid use after penile implant surgery
NCT ID NCT07246642
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting a long-lasting numbing medicine (Exparel mixed with bupivacaine) into the penis before placing an inflatable penile implant can reduce post-surgery pain and the need for opioid painkillers. One hundred men with erectile dysfunction who are getting a first-time implant will be randomly assigned to receive either the numbing injection or a placebo (salt water). The main goal is to see if the numbing injection leads to lower pain scores and less opioid use after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Exparel (bupivacaine) mixture
- What this could lead to
- If it works, this could provide a better way to manage pain after penile implant surgery and reduce the need for opioid painkillers.
- What could go wrong
- This is a small, early-phase study (100 people) testing a pain management technique, not a cure. The numbing effect may not be significantly better than a placebo, and individual results may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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