Can a simple injection before hysterectomy ease Post-Op pain?

NCT ID NCT05969457

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting a local anesthetic (ropivacaine) into the vagina before making the incision for a hysterectomy can reduce pain after surgery. 108 women scheduled for vaginal hysterectomy will be randomly assigned to receive either the anesthetic or a placebo (salt water) while under general anesthesia. The main goal is to see if the anesthetic group reports less pain in the hours after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ropivacaine (a local anesthetic)

What this could lead to

If it works, this could provide a simple way to reduce post-surgery pain for women undergoing vaginal hysterectomy.

What could go wrong

This is a relatively small, early-phase trial. The benefit may be small or not apply to all patients. There is always a risk of side effects from the anesthetic.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chu Rouen

    RECRUITING

    Rouen, 76031, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Gh Le Havre

    RECRUITING

    Le Havre, 76083, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact