New nerve block or drug: which eases pain after pituitary surgery?
NCT ID NCT06639659
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two approaches—a nerve block and a sedative drug—to reduce pain and improve the surgical field during trans-nasal endoscopic pituitary surgery. About 69 adults will be randomly assigned to receive either a sphenopalatine ganglion block, dexmedetomidine, or standard general anesthesia. The goal is to see which method provides better pain relief and less bleeding during and after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sphenopalatine ganglion block (nerve block procedure) and dexmedetomidine (drug)
What this could lead to
If successful, this could point to a better way to manage pain and reduce bleeding during pituitary surgery, improving recovery and comfort.
What could go wrong
This is a small, early-stage trial with only 69 participants, so results may not apply to everyone. Both methods have risks, such as side effects from the drug or complications from the nerve block.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Zagazig Univesity Hospital
Zagazig, Egypt