Numbing shot before fibroid surgery may cut pain and opioid use

NCT ID NCT06429163

First seen Jan 07, 2026 · Last updated Jun 19, 2026 · Updated 27 times

Summary

This study tested whether injecting a numbing medicine (ropivacaine) into the belly and around a nerve bundle before fibroid removal surgery could reduce pain afterward. 207 women having laparoscopic myomectomy were randomly assigned to get the numbing drug or a placebo. The main goal was to see if pain scores were lower 4 hours after surgery.

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Contacts and locations

Locations

  • Saint Petersburg State University Hospital

    Saint Petersburg, Russia

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ropivacaine

What this could lead to

If it works, this could offer a simple way to reduce pain and opioid use after laparoscopic fibroid surgery.

What could go wrong

This is a completed early-stage study. The results may not apply to all patients or surgeries, and the numbing effect may be limited.

Conditions

The condition(s) this trial relates to.

leiomyoma Pain, Postoperative uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.