New pain test battery could speed up drug development
NCT ID NCT07549490
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This pilot study will test a new method to see how two pain medicines, naproxen and pregabalin, work in healthy adults. Up to 25 participants will receive each medicine and a placebo in random order. They will undergo several short, controlled pain tests, like a cold water hand bath and a temporary sunburn-like skin sensitivity. The goal is to see if this testing approach can tell the difference between medicines that work in the brain versus those that reduce inflammation. This study is not expected to help participants directly but may improve how future pain treatments are tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naproxen and pregabalin
What this could lead to
If successful, this approach could help researchers test new pain treatments more efficiently in early studies.
What could go wrong
This is a very small pilot study in healthy adults, not patients. It is designed to test a method, not to prove any treatment works.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••