Brain scans reveal how fear of movement changes pain response
NCT ID NCT07688525
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study investigates how a person's beliefs about pain, such as fear of movement (kinesiophobia), influence brain activity during pain. Healthy adults will have a capsaicin cream applied to their forearm to cause temporary, moderate pain while researchers measure brain signals using non-invasive magnetic stimulation. The goal is to see if people with higher fear of movement show different brain responses to pain, which could help explain why pain affects people differently.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Topical capsaicin cream (1%)
- What this could lead to
- If it works, this could help explain why people respond differently to pain and point toward personalized approaches for pain management.
- What could go wrong
- This is a small, early-stage study in healthy volunteers using temporary pain, so results may not apply to people with chronic pain or other conditions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Université de Sherbrooke - Campus de la santé
Sherbrooke, Quebec, J1H 5H3, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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