New pill tested to tame deadly Virus-Linked inflammation

NCT ID NCT06052618

Summary

This study is testing an oral drug called pacritinib for two rare, severe inflammatory diseases caused by the Kaposi sarcoma herpesvirus (KSHV) in people living with HIV. Up to 75 adults with either KSHV-associated multicentric Castleman disease (MCD) or KSHV inflammatory cytokine syndrome (KICS) will take the pill twice daily for up to 24 weeks. The main goal is to see if the drug can control the dangerous inflammation and provide clinical benefit.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.