Could a single chemo drug replace the standard doublet for some ovarian cancers?

NCT ID NCT07401654

First seen Feb 14, 2026 · Last updated May 12, 2026 · Updated 14 times

Summary

This study compares two chemotherapy approaches for women with advanced ovarian cancer that has a high level of the PARK2 gene. One group gets the standard two-drug combo (paclitaxel plus carboplatin), while the other gets only paclitaxel. The goal is to see if the single drug works just as well but causes fewer side effects and delays resistance to platinum drugs. About 60 women will take part in this phase 2 trial.

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