New combo therapy shows promise for rare, aggressive skin cancer

NCT ID NCT03921008

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests giving the chemotherapy drug paclitaxel before and during radiation therapy for people with cutaneous angiosarcoma, a rare and aggressive skin cancer. The goal is to shrink the tumor before surgery and improve how long patients live without the cancer coming back. About 20 participants will receive the treatment and be followed for outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Paclitaxel (chemotherapy) and radiation therapy
What this could lead to
If successful, this combination could become a standard treatment to control cutaneous angiosarcoma before surgery, potentially improving survival rates.
What could go wrong
This is an early-phase trial with only 20 participants, so results may not apply broadly. Chemotherapy and radiation have significant side effects, and the cancer may still recur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.