New pill combo aims to fight stomach cancer when first treatment fails

NCT ID NCT07552402

First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether taking oral paclitaxel plus fruquintinib can help people with advanced stomach or gastroesophageal junction cancer after their first treatment stops working. About 150 adults will receive either the new drug combo or standard chemotherapy chosen by their doctor. The main goal is to see how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oral paclitaxel solution plus fruquintinib

What this could lead to

If successful, this could provide a new second-line treatment option for advanced gastric cancer, potentially slowing tumor growth and improving survival.

What could go wrong

This is an early-stage trial with only 150 participants, so results may not apply to all patients. The combination may cause side effects like toxicity, and it may not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED GASTRIC ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baotou Cancer Hospital

    RECRUITING

    Baotou, Inner Mongolia, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Harbin Medical University

    RECRUITING

    Harbin, Heilongjiang, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••