A gentler numbing shot for eyelid surgery? trial tests four tweaks to lidocaine.
NCT ID NCT07734740
First seen Jul 29, 2026 · Last updated Aug 04, 2026 · Updated 3 times
Summary
This trial tests whether warming lidocaine or adding sodium bicarbonate, hyaluronidase, or tranexamic acid can make the numbing injection less painful and reduce bleeding during upper eyelid surgery. About 80 adults having bilateral blepharoplasty will receive different mixtures on each side of the face to compare effects. The goal is to find a simple way to improve comfort and safety during this common procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lignocaine (lidocaine) with additives: sodium bicarbonate, warming, hyaluronidase, or tranexamic acid
- What this could lead to
- If it works, this could point toward a more comfortable and safer local anaesthesia method for eyelid surgery.
- What could go wrong
- This is a small pilot trial, so results may not apply to all patients. Some additives may cause irritation or allergic reactions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alice Ho Miu Ling Nethersole Hospital
Hong Kong, Hong Kong
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CUHK Medical Centre
Hong Kong, Hong Kong
-
Prince of Wales Hospital
Hong Kong, Hong Kong
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