Heart stent showdown: CT vs ultrasound in major trial

NCT ID NCT05253677

First seen Jan 21, 2026 · Last updated May 13, 2026 · Updated 19 times

Summary

This study tests whether using a CT scan before and during a heart stent procedure works as well as using an ultrasound probe inside the artery. About 1,090 adults with narrowed heart arteries will be randomly assigned to one of the two imaging methods. The main goal is to see if the CT-guided approach prevents heart attacks, heart-related death, or the need for repeat procedures as effectively as the ultrasound-guided approach.

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Contacts and locations

Locations

  • Aarhus Universitetshospital

    Aarhus, 8200, Denmark

  • Aichi Medical University

    Aichi, Japan

  • Azienda Ospedaliero Universitaria di Ferrara

    Cona, 44124, Italy

  • Barts Health NHS Trust

    London, E1 1FR, United Kingdom

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Centre Hospitalier Universitaire de Lille

    Lille, 59037, France

  • Centro Cardiologico Monzino S.P.A.

    Milan, Italy

  • Freeman Hospital

    Newcastle, NE7 7DN, United Kingdom

  • Gentofte hospital

    Gentofte Municipality, Hellerup, 2900, Denmark

  • Golden Jubilee National Hospital

    Clydebank, G81 4DY,, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust

    London, United Kingdom

  • Hartcentrum ZNA Antwerp

    Antwerp, 2000, Belgium

  • Humanitas University

    Milan, 20090, Italy

  • Liverpool Heart and Chest Hospital

    Liverpool, L14 3PE, United Kingdom

  • Medical Imaging Centre, Semmelweis University

    Budapest, 1082, Hungary

  • Minneapolis Heart Institute Foundation

    Minneapolis, Minnesota, 55407, United States

  • OLV Hospital

    Aalst, 9300, Belgium

  • Ospedale Galeazzi Sant'Ambrogio

    Milan, 20149, Italy

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • St George's University Hospitals NHS Foundation Trust

    London, ,SW17 0QT, United Kingdom

  • St. Francis Hospital & Heart Center

    Roslyn, New York, 11576, United States

  • UZ Brussels

    Jette, Brussels Capital, 1090, Belgium

  • University Hospitals Dorset NHS Foundation Trust, Poole Hospital

    Poole, Dorset, BH15 2JB, United Kingdom

Conditions

Explore the condition pages connected to this study.