Worm enzyme trial hopes to tame Crohn's Flare-Ups

NCT ID NCT02281916

First seen Dec 26, 2025 · Last updated May 20, 2026 · Updated 26 times

Summary

This early study tested whether a protein from a parasite (P28GST) is safe for people with moderate Crohn's disease. Ten adults with ileal or ileo-colic Crohn's received the treatment before or after bowel surgery. The goal was to see if it could control inflammation without causing serious side effects. Results focus on safety and changes in immune markers.

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Contacts and locations

Locations

  • CHRU, Hôpital Claude Huriez

    Lille, 59037, France

  • Centre Hospitalier Dunkerque

    Dunkirk, France

  • Centre Hospitalier de Boulogne

    Boulogne-sur-Mer, France

  • Centre Hospitalier,

    Valenciennes, France

  • Centre hospitalier

    Amiens, France

Conditions

Explore the condition pages connected to this study.