Can a 'Love Hormone' spray help schizophrenia symptoms?
NCT ID NCT07265180
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an oxytocin nasal spray, given before mindfulness-based group therapy, can reduce negative symptoms in people with schizophrenia. Negative symptoms include lack of motivation, social withdrawal, and reduced emotional expression. The trial will compare two different doses of oxytocin against a placebo in 120 participants, and will also look at genetic factors that might influence the response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oxytocin nasal spray
- What this could lead to
- If it works, this could point toward a better way to reduce negative symptoms like social withdrawal and lack of motivation in schizophrenia.
- What could go wrong
- This is an early-stage trial with only 120 people. Previous results have been inconsistent, and the effect may depend on individual genetics or context.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Campus Charité Mitte
RECRUITINGBerlin, State of Berlin, 12203, Germany
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