Can a 'Love Hormone' spray help schizophrenia symptoms?

NCT ID NCT07265180

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an oxytocin nasal spray, given before mindfulness-based group therapy, can reduce negative symptoms in people with schizophrenia. Negative symptoms include lack of motivation, social withdrawal, and reduced emotional expression. The trial will compare two different doses of oxytocin against a placebo in 120 participants, and will also look at genetic factors that might influence the response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxytocin nasal spray

What this could lead to

If it works, this could point toward a better way to reduce negative symptoms like social withdrawal and lack of motivation in schizophrenia.

What could go wrong

This is an early-stage trial with only 120 people. Previous results have been inconsistent, and the effect may depend on individual genetics or context.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Campus Charité Mitte

    RECRUITING

    Berlin, State of Berlin, 12203, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••