Love hormone nasal spray tested for borderline personality disorder
NCT ID NCT02225600
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 31 times
Summary
This pilot study tested whether a nasal spray containing oxytocin, sometimes called the 'love hormone,' could improve trust and cooperation in people with borderline personality disorder (BPD). Forty participants (some with BPD, some healthy) played a trust game after receiving either oxytocin or a placebo. The study aimed to see if oxytocin could normalize brain activity and behavior during the game. However, the study was suspended, so results are limited.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oxytocin (nasal spray)
What this could lead to
If it works, this could point toward a way to help people with borderline personality disorder feel more trusting and cooperative in social situations.
What could go wrong
This is a very small pilot study that has been suspended. It only looks at short-term effects in a lab setting, so results may not apply to real life or lead to a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.