Oxygen therapy shows promise for rare childhood movement attacks

NCT ID NCT06248645

First seen Apr 30, 2026 · Last updated Apr 30, 2026

Summary

This study tested whether breathing high-flow oxygen can quickly stop dystonic and plegic attacks in children with alternating hemiplegia of childhood (AHC), a rare genetic disorder causing temporary paralysis and muscle spasms. Twenty-four participants used oxygen or a placebo during attacks over five weeks. The goal was to see if more attacks stopped within 30 minutes with oxygen, offering a potential fast-acting treatment for these disabling episodes.

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Contacts and locations

Locations

  • HCL LYON

    Lyon, France

  • Hôpital Pitié Salpêtrière

    Paris, 75013, France

Conditions

Explore the condition pages connected to this study.