Oxygen may halt debilitating attacks in rare childhood disorder

NCT ID NCT06248645

First seen Apr 30, 2026 · Last updated Jun 15, 2026 · Updated 11 times

Summary

This study tested whether breathing high-flow oxygen can quickly stop dystonic (stiffening) and plegic (paralysis) attacks in children with alternating hemiplegia of childhood, a rare genetic condition. Twenty-four participants used oxygen or a placebo at the start of an attack. The main goal was to see if more attacks stopped within 30 minutes over five weeks.

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Contacts and locations

Locations

  • HCL LYON

    Lyon, France

  • Hôpital Pitié Salpêtrière

    Paris, 75013, France

Conditions

Explore the condition pages connected to this study.