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A smarter way to give oxygen during lung surgery? trial puts new monitor to the test

NCT ID NCT07720778

Disease control Sponsor: Konkuk University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial investigates whether using the Oxygen Reserve Index (ORI)—a noninvasive monitor that detects moderate oxygen excess—can help anesthesiologists fine-tune oxygen levels during one-lung ventilation. The goal is to reduce hyperoxemia (too much oxygen in the blood), which may cause complications after lung surgery. The study compares ORI-guided oxygen adjustment to standard care in adults undergoing elective lung surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ORI-Guided FiO2 Titration
What this could lead to
If successful, this approach could reduce hyperoxemia and its complications during one-lung ventilation, improving patient safety in thoracic surgery.
What could go wrong
This is a small, early-phase trial with 58 participants, so results may not apply broadly. The Oxygen Reserve Index is a newer tool, and its benefit over standard care is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 58 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged ≥19 years * Scheduled for elective lung surgery requiring one-lung ventilation * Written informed consent Exclusion Criteria: * Severe pulmonary hypertension. * Left ventricular systolic dysfunction. Withdrawal Criteria: * The participant or legally authorized representative requests withdrawal from the study. * An adverse event occurs that precludes continued participation in the study. * The planned surgery or study procedures are not performed (e.g., ORI monitoring is not applied or arterial blood gas analysis is not performed). * Perfusion Index is less than 2 during the study. * A major violation of the inclusion or exclusion criteria is identified after enrollment. * The participant fails to comply with the study protocol, potentially affecting the validity of the study outcomes. * Continued participation is considered not to be in the participant's best interest. * In the investigator's judgment, any other condition arises that makes continued participation inappropriate.

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Conditions

The condition(s) this trial relates to.

Hyperoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thoracic surgery with one-lung ventilation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Konkuk University Medical Center

    Seoul, Gwangjin-gu, 05030, South Korea

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