A smarter way to give oxygen during lung surgery? trial puts new monitor to the test

NCT ID NCT07720778

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial investigates whether using the Oxygen Reserve Index (ORI)—a noninvasive monitor that detects moderate oxygen excess—can help anesthesiologists fine-tune oxygen levels during one-lung ventilation. The goal is to reduce hyperoxemia (too much oxygen in the blood), which may cause complications after lung surgery. The study compares ORI-guided oxygen adjustment to standard care in adults undergoing elective lung surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ORI-Guided FiO2 Titration
What this could lead to
If successful, this approach could reduce hyperoxemia and its complications during one-lung ventilation, improving patient safety in thoracic surgery.
What could go wrong
This is a small, early-phase trial with 58 participants, so results may not apply broadly. The Oxygen Reserve Index is a newer tool, and its benefit over standard care is not yet proven.

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Conditions

The condition(s) this trial relates to.

Hyperoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Konkuk University Medical Center

    Seoul, Gwangjin-gu, 05030, South Korea

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