Baby breathing breakthrough? study tests oxygen flow in intubation
NCT ID NCT05967507
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether using a low flow of oxygen during a breathing tube placement in babies works as well as a high flow. About 1,192 newborns and infants up to 52 weeks old will take part. The goal is to see if the first attempt at placing the tube is just as successful with less oxygen.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- supplemental oxygen (low-flow vs high-flow)
- What this could lead to
- If low-flow oxygen works as well as high-flow, it could simplify and reduce costs for infant intubation procedures.
- What could go wrong
- This is an early-stage study comparing two oxygen delivery methods, not testing a new treatment. Results may show no meaningful difference or that low-flow is less safe.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHUV Centre Hospitalier Universitaire Vaudois
ACTIVE_NOT_RECRUITINGLausanne, 1011, Switzerland
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Department of Cardiac Anesthesiology and Intensive Care Medicine, Charité Universitätsmedizin
RECRUITINGBerlin, Germany
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Dept. Anesthesia, Montreal Children's Hospital, McGill University Health Centre
RECRUITINGMontreal, Canada
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Dept. Anesthesia, The Hospital for Sick Children
RECRUITINGToronto, Ontario, Canada
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Hospital Municipal Infantil Menino Jesus, Servicos Medicos de Anestesia
RECRUITINGSão Paulo, São Paulo, Brazil
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IRCCS Istituto Giannina Gaslini
RECRUITINGGenova, 16147, Italy
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Inselspital
RECRUITINGBern, 3010, Switzerland
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Kantonsspital Aarau, KSA
RECRUITINGAarau, Canton of Aargau, Switzerland
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Luzerner Kantonsspital
RECRUITINGLucerne, Canton of Lucerne, 6004, Switzerland
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Perth Children's Hospital
RECRUITINGPerth, Western Australia, 6009, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI read ultrasound to ensure a clear airway?
- Can a camera guide safer breathing tubes during endoscopy?
- Could a single device make emergency intubation faster and safer?
- Can a nasal cannula outperform a face mask in keeping patients oxygenated during emergency intubation?
- Could a simple valve make manual ventilation safer during surgery?
- Scope-Guided tube swap may cut time without oxygen