Baby breathing breakthrough? study tests oxygen flow in intubation

NCT ID NCT05967507

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using a low flow of oxygen during a breathing tube placement in babies works as well as a high flow. About 1,192 newborns and infants up to 52 weeks old will take part. The goal is to see if the first attempt at placing the tube is just as successful with less oxygen.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
supplemental oxygen (low-flow vs high-flow)
What this could lead to
If low-flow oxygen works as well as high-flow, it could simplify and reduce costs for infant intubation procedures.
What could go wrong
This is an early-stage study comparing two oxygen delivery methods, not testing a new treatment. Results may show no meaningful difference or that low-flow is less safe.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHUV Centre Hospitalier Universitaire Vaudois

    ACTIVE_NOT_RECRUITING

    Lausanne, 1011, Switzerland

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Department of Cardiac Anesthesiology and Intensive Care Medicine, Charité Universitätsmedizin

    RECRUITING

    Berlin, Germany

  • Dept. Anesthesia, Montreal Children's Hospital, McGill University Health Centre

    RECRUITING

    Montreal, Canada

  • Dept. Anesthesia, The Hospital for Sick Children

    RECRUITING

    Toronto, Ontario, Canada

  • Hospital Municipal Infantil Menino Jesus, Servicos Medicos de Anestesia

    RECRUITING

    São Paulo, São Paulo, Brazil

  • IRCCS Istituto Giannina Gaslini

    RECRUITING

    Genova, 16147, Italy

  • Inselspital

    RECRUITING

    Bern, 3010, Switzerland

  • Kantonsspital Aarau, KSA

    RECRUITING

    Aarau, Canton of Aargau, Switzerland

  • Luzerner Kantonsspital

    RECRUITING

    Lucerne, Canton of Lucerne, 6004, Switzerland

  • Perth Children's Hospital

    RECRUITING

    Perth, Western Australia, 6009, Australia

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