54,000 patients to reveal the safest oxygen level during surgery
NCT ID NCT07224243
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will look at 54,000 adults having surgery with general anesthesia to see how different oxygen levels affect their recovery. Patients will receive lower, intermediate, or higher oxygen during their operation. The goal is to find which oxygen level reduces the risk of organ injury or death within 30 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oxygen (different concentrations during anesthesia)
- What this could lead to
- If it succeeds, this could identify the best oxygen level to use during surgery to reduce complications like kidney or lung injury.
- What could go wrong
- This is an observational-style trial comparing existing practices, not testing a new drug. Results may show no clear difference or be influenced by other factors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68105, United States
-
University of Michigan Hospital
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
-
University of Utah Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
-
Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37212, United States
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