54,000 patients to reveal the safest oxygen level during surgery
NCT ID NCT07224243
First seen Nov 04, 2025 · Last updated Jun 20, 2026 · Updated 34 times
Summary
This study will look at 54,000 adults having surgery with general anesthesia to see how different oxygen levels affect their recovery. Patients will receive lower, intermediate, or higher oxygen during their operation. The goal is to find which oxygen level reduces the risk of organ injury or death within 30 days after surgery.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Michigan Hospital
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Utah Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37212, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxygen (different concentrations during anesthesia)
What this could lead to
If it succeeds, this could identify the best oxygen level to use during surgery to reduce complications like kidney or lung injury.
What could go wrong
This is an observational-style trial comparing existing practices, not testing a new drug. Results may show no clear difference or be influenced by other factors.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.