New study to reveal hidden toll of breast cancer drugs on fertility

NCT ID NCT07527819

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 75 women aged 18-42 with early-stage triple-negative breast cancer who are receiving chemotherapy plus immunotherapy before surgery. Researchers will measure hormone levels, track menstrual patterns, and use questionnaires to see how treatment affects ovarian function and fertility. No extra drugs are given—participants receive standard care. Results may help doctors better counsel patients about fertility risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could help doctors understand the impact of these treatments on ovarian health and fertility, guiding future care and counseling for young women with breast cancer.

What could go wrong

This is an observational study, not a treatment trial. It only collects data and does not test any new therapy, so it cannot directly improve outcomes. Results may take years to influence practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Inflammation primary ovarian failure triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chris O'Brien Lifehouse

    Camperdown, New South Wales, 2050, Australia

    Contact Email: •••••@•••••

    Contact

  • Eastern Health

    Box Hill, Victoria, 3128, Australia

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  • Icon Cancer Centre

    Hobart, Tasmania, 7000, Australia

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  • Lyell McEwin Hospital

    Adelaide, South Australia, 5112, Australia

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  • Mater Hospital Sydney

    Sydney, New South Wales, 2060, Australia

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  • Monash Health

    Clayton, Victoria, 3168, Australia

    Contact Email: •••••@•••••

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  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

    Contact Email: •••••@•••••

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  • Royal Melbourne Hospital

    Melbourne, Victoria, 3052, Australia

    Contact Email: •••••@•••••

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  • Sir Charles Gairdner Hospital

    Nedlands, Washington, 6009, Australia

    Contact Email: •••••@•••••

    Contact