Can an Immune-Boosting drug help a cancer pill fight ovarian cancer better?
NCT ID NCT04034927
Summary
This study is testing if a combination of two drugs works better than one alone to control recurrent ovarian, fallopian tube, or primary peritoneal cancer. It compares a standard targeted drug (olaparib) against that same drug plus an immunotherapy drug (tremelimumab). The main goals are to see if the combination is safe and if it can keep the cancer from growing longer than the single drug.
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Contacts and locations
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Locations
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Augusta University Medical Center
Augusta, Georgia, 30912, United States
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Hartford Hospital
Hartford, Connecticut, 06102, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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UCHealth University of Colorado Hospital
Aurora, Colorado, 80045, United States
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UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio, 44122, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106, United States
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
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VCU Massey Comprehensive Cancer Center
Richmond, Virginia, 23298, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Women and Infants Hospital
Providence, Rhode Island, 02905, United States
Conditions
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