Promising combo therapy targets fluid buildup in recurrent ovarian cancer

NCT ID NCT04919629

First seen Apr 09, 2026 · Last updated May 14, 2026 · Updated 5 times

Summary

This study tests whether adding an experimental drug (APL-2) to standard immunotherapy (pembrolizumab) and/or a targeted therapy (bevacizumab) can better control fluid buildup and tumor growth in people whose ovarian, fallopian tube, or peritoneal cancer has returned. About 60 adults with recurrent cancer and persistent fluid in the abdomen or chest will be randomly assigned to one of three treatment groups. The goal is to see if the combinations are safer and more effective than bevacizumab alone.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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