New weapon in ovarian cancer fight? major trial tests Immune-Boosting drug

NCT ID NCT04498117

Ongoing Disease control Sponsor: CanariaBio Inc. Source: ClinicalTrials.gov ↗

First seen Apr 07, 2026 · Last updated Apr 18, 2026 · Updated 1 time

Summary

This large, late-stage study is testing whether adding an immunotherapy drug called oregovomab to standard chemotherapy helps people with advanced ovarian, fallopian tube, or peritoneal cancer live longer without their cancer getting worse. About 615 participants who have already had surgery will receive either the standard chemo plus the new drug or just the standard chemo plus a placebo. The main goal is to see if the drug combination can better control the disease and delay its return.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AdventHealth Orlando

Orlando, Florida, 32804, United States
All India Institute of Medical Services

Delhi, India
Asan Medical Center

Seoul, South Korea
Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo)

Monza, Italy
Bacs-Kiskun Megyei Oktatokorhaz

Kecskemét, Hungary
CEMAIC - Centro Medico Privado

Córdoba, Córdoba Province, 2941, Argentina
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia

Santo André, Brazil
CER San Juan Centro Polivalente de Asistencia e Inv. Clinica

San Juan, Argentina
CHUM Centre de Recherche (affiliated with University of Montreal)

Montreal, Quebec, H2X 3E4, Canada
CHUS - Hôpital Fleurimont

Sherbrooke, Quebec, J1H 5N4, Canada
Carilion Clinic Gynecological Oncology

Roanoke, Virginia, 24106, United States
Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa - Hospital Mae de Deus

Porto Alegre, Brazil
Centro Potosino de Investigación Medica S.C.

San Luis Potosí City, Mexico
Centro de Investigación Clínica Bradford Hill

Santiago, Chile
Centro de Pesquisas Clinica Reichow

Blumenau, Brazil
City of Health Hospital at Laval (Cité de la Santé de Laval)

Laval, Quebec, H7M 3L9, Canada
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Cleveland Clinic Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Hillcrest Hospital

Mayfield Heights, Ohio, 44124, United States
Clinical Medical Research S.C.

Orizaba, Veracruz, Mexico
Clinicas Viedma S.A.

Viedma, R8500, Argentina
Clinique CHC MontLégia

Liège, Belgium
Cliniques Universitaires Saint-Luc

Brussels, Belgium
Clínica São Germano - Oncologia

São Paulo, Brazil
Clínica Universitaria Privada Reina Fabiola

Córdoba, Córdoba Province, Argentina
Contra Costa Oncology

Walnut Creek, California, 94598, United States
Debreceni Egyetem

Debrecen, Hungary
Deenanath Mangeshkar Hospital

Pune, India
Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet

Budapest, Hungary
Duke University

Durham, North Carolina, 27710, United States
Duke Women's Cancer Care Raleigh

Raleigh, North Carolina, 27607, United States
Epic Care

Pleasant Hill, California, 94523, United States
Fakultni nemocnice Bulovka

Prague, Czechia
Fakultni nemocnice Hradec Kralove

Hradec Králové, 500 05, Czechia
Fakultni nemocnice Kralovske Vinohrady

Prague, Czechia
Fakultni nemocnice v Motole

Prague, Czechia
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Rome, Rome, 00168, Italy
Fortis Hospital

Noida, India
Fortis Hospital Ltd

Bangalore, India
Fortis Hospital Ltd

Bengaluru, India
Fundação Doutor Amaral Carvalho

São Paulo, Brazil
Grandview Medical Center/Kettering Medical Center

Kettering, Ohio, 45429, United States
Honor Health

Phoenix, Arizona, 85016, United States
Hospital Clinic de Barcelona

Barcelona, Catalonia, Spain
Hospital Universitari Vall d'Hebron

Barcelona, Catalonia, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, Spain
ICO l'Hospitalet-Hospital Duran i Reynals

L'Hospitalet de Llobregat, Spain
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Instituto Valenciano de Oncologia IVO

Valencia, Spain
Investigacion Onco Farmaceutica S. de R.L. de C.V. (OncoTech)

La Paz, 23040, Mexico
John Muir Health Clinical Research Center

Concord, California, 94520, United States
John Muir Health Gynecologic Cancer Services

Walnut Creek, California, 94598, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Riverside Medical Center

Riverside, California, 95505, United States
Kaiser Permanente Southern California

Irvine, California, 92120, United States
Kapiolani Medical Center for Women and Children/University of Hawaii

Honolulu, Hawaii, 96826, United States
Koo Foundation Sun Yat-Sen Cancer Center

Taipei, Taiwan
Korea University Guro Hospital

Seoul, South Korea
Lahey Hospital and Medical Center

Burlington, Massachusetts, 01805, United States
Lewis Cancer & Research Pavilion at St. Joseph's Candler

Savannah, Georgia, 31405, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
Magee Women's Hospital of UPMC

Pittsburgh, Pennsylvania, 15213, United States
Magyar Honvedseg Egeszsegugyi Kozpont

Budapest, Hungary
Max Super Specialty Hospital

Mohali, India
McGill University Health Centre/Glen Site/ Royal Victoria Hospital

Montreal, Quebec, H4A 3J1, Canada
Memorial Herman Hospital

Houston, Texas, 77030, United States
Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States
MetroWest Medical Center

Farmington, Massachusetts, 01702, United States
Minnesota Oncology Hematology

Edina, Minnesota, 55435, United States
Minnesota Oncology Hematology

Minneapolis, Minnesota, 55404, United States
Minnesota Oncology Hematology

Saint Paul, Minnesota, 55102, United States
Minnesota Oncology Hematology - Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Montefiore Medical Center PRIME

The Bronx, New York, 10461, United States
Moores UC San Diego Cancer Center

La Jolla, California, 92093, United States
Mount Sinai - PRIME

Lake Success, New York, 10019, United States
Mount Sinai The Blavatnik Family Chelsea Medical Center

New York, New York, 10011, United States
MultiCare Institute for Research and Innovation

Puyallup, Washington, 98372, United States
MultiCare Regional Cancer Center - Auburn

Auburn, Washington, 98001, United States
MultiCare Regional Cancer Center - Tacoma

Tacoma, Washington, 98405, United States
MultiCare Regional Cancer Center-Gig Harbor Medical Park

Gig Harbor, Washington, 98335, United States
National Cancer Center

Goyang, South Korea
National Cheng Kung University Hospital

Tainan, 70457, Taiwan
National Taiwan University Hospital

Taipei, Taiwan, Taiwan
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
Northwest Cancer Specialists, P.C.-Portland-Rose Quarter

Portland, Oregon, 97227, United States
Ohio State University Wexner Medical Center

Columbus, Ohio, 43026, United States
Oklahoma Cancer Specialist and Research Institution, LLC

Tulsa, Oklahoma, 74146, United States
Oncosite - Centro de Pesquisa Clinica e Oncologia

Guimarães, Brazil
Park Nicollet Frauenshuh Cancer Center

Saint Louis Park, Minnesota, 55426, United States
Parkview Research Center

Fort Wayne, Indiana, 46845, United States
Portsmouth Regional Hospital

Portsmouth, New Hampshire, 03801, United States
Queen Elizabeth II Health Sciences Centre

Halifax, Nova Scotia, B3H 2Y9, Canada
Ruby Hall Clinic

Pune, India
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
SCC at St. John's Medical Center

Westlake, Ohio, 44145, United States
SCC at UH Geauga Medical Center

Chardon, Ohio, 44024, United States
SMIQ S. de R.L. de C.V.

Querétaro, Mexico
Samsung Medical Center

Seoul, South Korea
Sanatorio Parque S.A

Salta, Salta Province, 4400, Argentina
Sanatorio de la Mujer

Rosario, Rosario, 2000, Argentina
Sanford Research/USD-Sioux Falls

Sioux Falls, South Dakota, 57104, United States
Seoul National University Bundang Hospital

Seongnam, South Korea
Seoul National University Hospital

Seoul, South Korea
Severance Hospital Yonsei University Health System

Soeul, South Korea
Severance Hospital, Yonsei University Health System

Seoul, South Korea
Smilow Cancer Hospital

New Haven, Connecticut, 06510, United States
Sociedad de Investigaciones Medicas Limitada

Temuco, Chile
Sparrow Hospital

Lansing, Michigan, 48219, United States
St. Joseph Mercy Hospital

Ann Arbor, Michigan, 48106, United States
Stony Brook University Hospital

Stony Brook, New York, 11794, United States
Sushrut Hospital

Mumbai, India
Taichung Veterans General Hospital

Taichung, Taiwan
Taipei Veterans General Hospital

Taipei County, Taipei, Taiwan
Texas Oncology San Antonio Medical Center

San Antonio, Texas, 78240, United States
Texas Oncology, P.A.

Dallas, Texas, 75231, United States
Texas Oncology, P.A. - Austin

Austin, Texas, 78731, United States
Texas Oncology, P.A. - Fort Worth

Fort Worth, Texas, 76104, United States
The Catholic University of Korea, Seoul St. Mary's Hospital

Seoul, South Korea
The Queens Medical Center

Honolulu, Hawaii, 96813, United States
The University of Arizona Cancer Center

Tucson, Arizona, 85724, United States
The Valley Hospital (Valley Health)

Paramus, New Jersey, 07450, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
Tufts Medical Center Cancer Center in Stoneham

Stoneham, Massachusetts, 02180, United States
UH Minoff Health Center - Seidman

Orange, Ohio, 44122, United States
UMass Memorial Medical Center

Worcester, Massachusetts, 01605, United States
UPMC Hillman Cancer Center at UPMC Passavant

Pittsburgh, Pennsylvania, 15237-9643, United States
Universidad Autonoma de Nuevo Leon, Hospital Universitario Dr. Jose Eleuterio Gonzalez

Monterrey, Mexico
University Hospitals of Cleveland

Cleveland, Ohio, 44106, United States
University of California, Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Colorado Health

Aurora, Colorado, 80045, United States
University of Connecticut Health Center

Farmington, Connecticut, 06030, United States
University of Minnesota Health - Maple Grove Clinic

Maple Grove, Minnesota, 55369, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Virginia Health Systems

Charlottesville, Virginia, 22903, United States
University of Wisconsin

Madison, Wisconsin, 53792, United States
Università Campus Bio-Medico di Roma

Rome, Italy
VCU Massey Cancer Center

Richmond, Virginia, 23298, United States
Virginia Cancer Specialists

Fairfax, Virginia, 21055, United States
Virginia Oncology Associates - Hampton

Norfolk, Virginia, 23502, United States
Vseobecna fakultni nemocnice v Praze

Prague, Czechia
Willamette Valley Cancer Institute and Research Center

Eugene, Oregon, 97401, United States
Women & Infants Hospital of Rhode Island

Providence, Rhode Island, 02905, United States
Women's Cancer Care/Mary Bird Perkins Cancer Center

Covington, Louisiana, 70433, United States
Women's Cancer Florida/Women's Cancer Associates

St. Petersburg, Florida, 33701, United States
Womens Cancer Care Associates

Albany, New York, 12208, United States
Yale University School of Medicine

New Haven, Connecticut, 06510, United States
ZNA Middelheim

Antwerp, Belgium
Zala Megyei Szent Rafael Korhaz

Zalaegerszeg, Hungary

Conditions

Explore the condition pages connected to this study.

CARCINOMA, OVARIAN EPITHELIAL FALLOPIAN TUBE ADENOCARCINOMA FALLOPIAN TUBE NEOPLASMS FALLOPIAN TUBE SEROUS ADENOCARCINOMA OVARIAN CANCER OVARIAN NEOPLASMS OVARIAN SEROUS ADENOCARCINOMA PERITONEAL CANCER PERITONEAL CARCINOMA PERITONEAL NEOPLASMS