Major cancer trial tests new drug combo for Tough-to-Treat ovarian cancer

NCT ID NCT01081262

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing which combination of chemotherapy drugs works best for women with a specific type of ovarian or fallopian tube cancer (mucinous adenocarcinoma). It compares two standard drug pairs, with or without an added drug (bevacizumab) that blocks tumor blood supply. The main goal is to see which treatment helps patients live longer and with a better quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
AdventHealth Hendersonville

Hendersonville, North Carolina, 28792, United States
AdventHealth Littleton

Littleton, Colorado, 80122, United States
AdventHealth Orlando

Orlando, Florida, 32803, United States
AdventHealth Parker

Parker, Colorado, 80138, United States
AdventHealth Porter

Denver, Colorado, 80210, United States
Alta Bates Summit Medical Center - Summit Campus

Oakland, California, 94609, United States
AnMed Health Cancer Center

Anderson, South Carolina, 29621, United States
AnMed Health Hospital

Anderson, South Carolina, 29621, United States
Ascension Saint Vincent Indianapolis Hospital

Indianapolis, Indiana, 46260, United States
Augusta University Medical Center

Augusta, Georgia, 30912, United States
Aultman Health Foundation

Canton, Ohio, 44710, United States
Aurora Medical Center in Summit

Summit, Wisconsin, 53066, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Bay Area Breast Surgeons Inc

Emeryville, California, 94608, United States
Bay Area Medical Center

Marinette, Wisconsin, 54143, United States
Bay Area Tumor Institute

Oakland, California, 94609, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Beacon Kalamazoo

Kalamazoo, Michigan, 49048, United States
Beebe Medical Center

Lewes, Delaware, 19958, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Bethesda North Hospital

Cincinnati, Ohio, 45242, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Boulder Community Foothills Hospital

Boulder, Colorado, 80303, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
Cancer Care Partners LLC

Mishawaka, Indiana, 46545, United States
Cancer Center of Acadiana

Lafayette, Louisiana, 70503, United States
Carle BroMenn Medical Center

Normal, Illinois, 61761, United States
Carle Cancer Institute Normal

Normal, Illinois, 61761, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Centra Alan B Pearson Regional Cancer Center

Lynchburg, Virginia, 24501, United States
Christiana Care - Union Hospital

Elkton, Maryland, 21921, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Columbus NCI Community Oncology Research Program

Columbus, Ohio, 43215, United States
Community Howard Regional Health

Kokomo, Indiana, 46904, United States
Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085, United States
Corewell Health Lakeland Hospitals - Niles Hospital

Niles, Michigan, 49120, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital

Saint Joseph, Michigan, 49085, United States
Danville Regional Medical Center

Danville, Virginia, 24541, United States
Doctors Hospital

Columbus, Ohio, 43228, United States
Doctors Medical Center- JC Robinson Regional Cancer Center

San Pablo, California, 94806, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
East Bay Radiation Oncology Center

Castro Valley, California, 94546, United States
El Camino Hospital

Mountain View, California, 94040, United States
Elkhart Clinic

Elkhart, Indiana, 46514-2098, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Epic Care Partners in Cancer Care

Emeryville, California, 94608, United States
Eureka Hospital

Eureka, Illinois, 61530, United States
Fairfield Medical Center

Lancaster, Ohio, 43130, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Center-Cancer Center Hazleton

Hazleton, Pennsylvania, 18201, United States
Geisinger Medical Group

State College, Pennsylvania, 16801, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States
Glacier Oncology PLLC

Kalispell, Montana, 59901, United States
Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Graham Hospital Association

Canton, Illinois, 61520, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Green Bay Oncology at Saint Vincent Hospital

Green Bay, Wisconsin, 54301-3526, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Heartland Cancer Research NCORP

Decatur, Illinois, 62526, United States
Hematology Oncology Associates of Fredericksburg Inc

Fredericksburg, Virginia, 22408, United States
Hematology and Oncology Associates-Oakland

Oakland, California, 94609, United States
Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124, United States
Holy Family Medical Center

Monmouth, Illinois, 61462, United States
Holy Family Memorial Hospital

Manitowoc, Wisconsin, 54221, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
IU Health La Porte Hospital

La Porte, Indiana, 46350, United States
Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States
Illinois CancerCare-Canton

Canton, Illinois, 61520, United States
Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare-Community Cancer Center

Normal, Illinois, 61761, United States
Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Havana

Havana, Illinois, 62644, United States
Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443, United States
Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare-Monmouth

Monmouth, Illinois, 61462, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois CancerCare-Peru

Peru, Illinois, 61354, United States
Illinois CancerCare-Princeton

Princeton, Illinois, 61356, United States
Illinois CancerCare-Spring Valley

Spring Valley, Illinois, 61362, United States
Illinois Valley Hospital

Peru, Illinois, 61354, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Iowa-Wide Oncology Research Coalition NCORP

Des Moines, Iowa, 50309, United States
Jefferson Abington Hospital

Abington, Pennsylvania, 19001, United States
John B Amos Cancer Center

Columbus, Georgia, 31904, United States
Kalispell Medical Oncology

Kalispell, Montana, 59901, United States
Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Knox Community Hospital

Mount Vernon, Ohio, 43050, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Licking Memorial Hospital

Newark, Ohio, 43055, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MU Health Care Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States
Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Mary Rutan Hospital

Bellefontaine, Ohio, 43311, United States
Mason District Hospital

Havana, Illinois, 62644, United States
Mcdonough District Hospital

Macomb, Illinois, 61455, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Hermann Texas Medical Center

Houston, Texas, 77030, United States
Memorial Hospital

Carthage, Illinois, 62321, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Mercy Cancer Center - Cape Girardeau

Cape Girardeau, Missouri, 63703, United States
Mercy Cancer Center-West Lakes

Clive, Iowa, 50325, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Mercy Medical Center-Sioux City

Sioux City, Iowa, 51102, United States
Mercy Medical Center-West Lakes

West Des Moines, Iowa, 50266, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Michiana Hematology Oncology PC-Elkhart

Elkhart, Indiana, 46514, United States
Michiana Hematology Oncology PC-Mishawaka

Mishawaka, Indiana, 46545, United States
Michiana Hematology Oncology PC-Plymouth

Plymouth, Indiana, 46563, United States
Michiana Hematology Oncology PC-Westville

Westville, Indiana, 46391, United States
Mid Dakota Clinic

Bismarck, North Dakota, 58501, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Montana Cancer Consortium NCORP

Billings, Montana, 59102, United States
Montana Cancer Specialists

Missoula, Montana, 59802, United States
Mount Carmel East Hospital

Columbus, Ohio, 43213, United States
Mount Carmel Health Center West

Columbus, Ohio, 43222, United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro

Jonesboro, Arkansas, 72401, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
North Suburban Medical Center

Thornton, Colorado, 80229, United States
Northeast Georgia Medical Center-Gainesville

Gainesville, Georgia, 30501, United States
Northern Indiana Cancer Research Consortium

South Bend, Indiana, 46628, United States
Northern Montana Hospital

Havre, Montana, 59501, United States
OSF Saint Francis Hospital and Medical Group

Escanaba, Michigan, 49829, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Pekin

Pekin, Illinois, 61554, United States
OSF Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States
Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa

Tulsa, Oklahoma, 74146, United States
Olive View-University of California Los Angeles Medical Center

Sylmar, California, 91342, United States
Ottawa Regional Hospital and Healthcare Center

Ottawa, Illinois, 61350, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Perry Memorial Hospital

Princeton, Illinois, 61356, United States
Pikeville Medical Center

Pikeville, Kentucky, 41501, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Rocky Mountain Oncology

Casper, Wyoming, 82609, United States
Rose Medical Center

Denver, Colorado, 80220, United States
Saint Alexius Medical Center

Bismarck, North Dakota, 58501, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
Saint Elizabeth Healthcare Edgewood

Edgewood, Kentucky, 41017, United States
Saint Francis Hospital

Greenville, South Carolina, 29601, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint Joseph Hospital - Cancer Centers of Colorado

Denver, Colorado, 80218, United States
Saint Joseph Regional Medical Center-Mishawaka

Mishawaka, Indiana, 46545, United States
Saint Joseph's Hospital and Medical Center

Phoenix, Arizona, 85013, United States
Saint Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States
Saint Luke's University Hospital-Bethlehem Campus

Bethlehem, Pennsylvania, 18015, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Mary's Hospital and Regional Medical Center

Grand Junction, Colorado, 81501, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Vincent Frontier Cancer Center

Billings, Montana, 59102, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301, United States
Saint Vincent Hospital Cancer Center at Oconto Falls

Oconto Falls, Wisconsin, 54154, United States
Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
Siouxland Regional Cancer Center

Sioux City, Iowa, 51101, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
South Bend Clinic

South Bend, Indiana, 46617, United States
Southeast Clinical Oncology Research Consortium NCORP

Winston-Salem, North Carolina, 27104, United States
Southern Ohio Medical Center

Portsmouth, Ohio, 45662, United States
Southwest Gynecologic Oncology Associates Inc

Albuquerque, New Mexico, 87106, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Springfield Regional Medical Center

Springfield, Ohio, 45504, United States
Stamford Hospital/Bennett Cancer Center

Stamford, Connecticut, 06904, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Sudarshan K Sharma MD Limited-Gynecologic Oncology

Hinsdale, Illinois, 60521, United States
Summa Health System - Akron Campus

Akron, Ohio, 44304, United States
Swedish American Hospital

Rockford, Illinois, 61104, United States
Swedish Medical Center

Englewood, Colorado, 80113, United States
The Hospital of Central Connecticut

New Britain, Connecticut, 06050, United States
The Mark H Zangmeister Center

Columbus, Ohio, 43219, United States
The Medical Center of Aurora

Aurora, Colorado, 80012, United States
Tom K Lee Inc

Oakland, California, 94609, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UF Health Cancer Institute - Gainesville

Gainesville, Florida, 32610, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Hawaii Cancer Center

Honolulu, Hawaii, 96813, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of South Alabama Mitchell Cancer Institute

Mobile, Alabama, 36688, United States
University of Tennessee - Knoxville

Knoxville, Tennessee, 37920, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0565, United States
Valley Medical Oncology Consultants-Castro Valley

Castro Valley, California, 94546, United States
Valley Medical Oncology Consultants-Fremont

Fremont, California, 94538, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Virtua Memorial

Mount Holly, New Jersey, 08060, United States
Virtua Voorhees

Voorhees Township, New Jersey, 08043, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Walter Reed National Military Medical Center

Bethesda, Maryland, 20889-5600, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne Memorial Hospital

Goldsboro, North Carolina, 27534, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Western States Cancer Research NCORP

Denver, Colorado, 80222, United States
Wilma Chan Highland Hospital

Oakland, California, 94602, United States
Women and Infants Hospital

Providence, Rhode Island, 02905, United States
Women's Cancer Center of Nevada

Las Vegas, Nevada, 89106, United States

Conditions

Explore the condition pages connected to this study.