Scientists test new drug to weaken ovarian cancer before surgery

NCT ID NCT02659241

Summary

This early study is testing if a drug called adavosertib, given before surgery, can affect the DNA of tumors in patients with advanced ovarian, fallopian tube, or primary peritoneal cancer. The main goal is to learn how the drug changes the cancer cells at a molecular level, which may help doctors understand how to plan better treatments in the future. It involves 38 participants who take the drug orally for a short period before their standard surgery.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • MD Anderson League City

    League City, Texas, 77573, United States

  • MD Anderson West Houston

    Houston, Texas, 77079, United States

  • MD Anderson in Sugar Land

    Sugar Land, Texas, 77478, United States

  • MD Anderson in The Woodlands

    Conroe, Texas, 77384, United States

  • Memorial Hermann Memorial City Medical Center

    Houston, Texas, 77024, United States

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97239, United States

  • The Woman's Hospital of Texas

    Houston, Texas, 77054, United States

Conditions

Explore the condition pages connected to this study.