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New Two-Punch combo tested for Tough-to-Treat ovarian cancer

NCT ID NCT04633239

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This early-phase study is testing the safety and best dose of two oral drugs, abemaciclib and olaparib, given together for ovarian cancer that has returned and is resistant to standard platinum-based chemotherapy. The goal is to see if combining these drugs, which work in different ways to stop cancer cell growth, is tolerable and shows signs of helping control the disease. The study will enroll about 42 adult women who have had 1 to 3 prior treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Los Angeles General Medical Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Hospital in Arizona

    ACTIVE_NOT_RECRUITING

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic in Florida

    RECRUITING

    Jacksonville, Florida, 32224-9980, United States

    Contact

    Contact Phone: •••-•••-••••

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-••••

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

    SUSPENDED

    New York, New York, 10032, United States

  • Northwestern University

    ACTIVE_NOT_RECRUITING

    Chicago, Illinois, 60611, United States

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UC Irvine Health/Chao Family Comprehensive Cancer Center

    RECRUITING

    Orange, California, 92868, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care

    RECRUITING

    Irvine, California, 92612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UM Sylvester Comprehensive Cancer Center at Coral Gables

    ACTIVE_NOT_RECRUITING

    Coral Gables, Florida, 33146, United States

  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach

    ACTIVE_NOT_RECRUITING

    Deerfield Beach, Florida, 33442, United States

  • UM Sylvester Comprehensive Cancer Center at Plantation

    ACTIVE_NOT_RECRUITING

    Plantation, Florida, 33324, United States

  • USC / Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-••••

  • University of Kansas Cancer Center

    SUSPENDED

    Kansas City, Kansas, 66160, United States

  • University of Kansas Cancer Center - Lee's Summit

    SUSPENDED

    Lee's Summit, Missouri, 64064, United States

  • University of Kansas Cancer Center - North

    SUSPENDED

    Kansas City, Missouri, 64154, United States

  • University of Kansas Cancer Center at North Kansas City Hospital

    SUSPENDED

    North Kansas City, Missouri, 64116, United States

  • University of Kansas Cancer Center-Overland Park

    SUSPENDED

    Overland Park, Kansas, 66210, United States

  • University of Kansas Clinical Research Center

    RECRUITING

    Fairway, Kansas, 66205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kansas Hospital-Indian Creek Campus

    SUSPENDED

    Overland Park, Kansas, 66211, United States

  • University of Kansas Hospital-Westwood Cancer Center

    SUSPENDED

    Westwood, Kansas, 66205, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33136, United States

  • University of Oklahoma Health Sciences Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia Cancer Center

    RECRUITING

    Charlottesville, Virginia, 22908, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University/Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Phone: •••-•••-••••

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

RECURRENT OVARIAN HIGH GRADE SEROUS ADENOCARCINOMA RECURRENT PLATINUM-RESISTANT OVARIAN CARCINOMA