New hope for Tough-to-Treat bone cancer?

NCT ID NCT04833582

Summary

This study tested the safety and early effectiveness of a new drug called azenosertib (ZN-c3) when given with an existing chemotherapy drug, gemcitabine. It involved 31 adults and teenagers (12+) whose osteosarcoma (a type of bone cancer) had come back or stopped responding to prior treatments. The main goals were to find a safe dose and see if the combination could help control the cancer.

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Contacts and locations

Locations

  • Site 0103

    Houston, Texas, 77030, United States

  • Site 0105

    New York, New York, 10065, United States

  • Site 0106

    Los Angeles, California, 90095, United States

  • Site 0107

    Cincinnati, Ohio, 45229, United States

  • Site 0122

    Seattle, Washington, 98195, United States

  • Site 0123

    Portland, Oregon, 97239, United States

  • Site 0124

    Oakland, California, 94609, United States

  • Site 0188

    Richmond, Virginia, 23298, United States

  • Site 0193

    Memphis, Tennessee, 38105, United States

  • Site 0195

    Santa Monica, California, 90403, United States

  • Site 0197

    Nashville, Tennessee, 37332, United States

  • Site 3601

    Lyon, 69008, France

  • Site 3602

    Marseille, 13385, France

  • Site 3604

    Bordeaux, 33000, France

  • Site 3605

    Toulouse, 31100, France

  • Site 3606

    Paris, 75248, France

  • University of Florida College of Medicine

    Gainesville, Florida, 32610, United States

Conditions

Explore the condition pages connected to this study.