Can genes predict rare bone fractures? new study investigates
NCT ID NCT04110795
First seen May 12, 2026 · Last updated May 12, 2026
Summary
This study aims to identify clinical and genetic risk factors for atypical femur fractures (AFFs) in people taking anti-resorptive therapy (ART) for osteoporosis. Researchers will compare 330 people who had an AFF with 660 people who did not, matching them by age, sex, race, and duration of ART use. The goal is to better personalize osteoporosis care by understanding who is at higher risk for this rare but serious fracture.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Adachi Medical Centre
Hamilton, Ontario, L8N 1Y2, Canada
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Bone Research & Education Centre
Oakville, Ontario, L6M 1M1, Canada
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University Health Network, TGH
Toronto, Ontario, M5G 2C4, Canada
Conditions
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