Early trial for brittle bone disease halted

NCT ID NCT05231668

Summary

This was an early, small study to check the safety of a single dose of an experimental drug called SAR439459 in adults with osteogenesis imperfecta (brittle bone disease). The main goal was to see if the drug was safe and how the body processed it, while also looking for early signs of effect on bone density. The study was terminated and only enrolled 16 participants.

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Contacts and locations

Locations

  • Baylor College of Medicine - Site Number:8400003

    Houston, Texas, 77030, United States

  • Bone Research and Education Centre_Site Number :1240003

    Oakville, Ontario, L6M 1M1, Canada

  • Cincinnati Children's Hospital Medical Center Site Number : 8400010

    Cincinnati, Ohio, 45229, United States

  • Department of Medicine/ School of Clinical Sciences at Monash Health Monash University_246 Clayton Road_Site Number :0360002

    Clayton, Victoria, 3168, Australia

  • Hopital Edouard Herriot _Site Number :2500002

    Lyon, 69003, France

  • Hopital Lariboisiere_Site Number :2500001

    Paris, 75010, France

  • Indiana University School of Medicine_Site Number: 8400002

    Indianapolis, Indiana, 46202, United States

  • Kennedy Krieger Institute_Site number 8400004

    Baltimore, Maryland, 21205, United States

  • Toronto general Hospital_Site Number :1240002

    Toronto, M5G 2C4, Canada

  • UCLA Health_Site Number: 8400006

    Los Angeles, California, 90095, United States

  • Vanderbilt University Site Number : 8400011

    Nashville, Tennessee, 37232, United States

  • Westmead Hospital_Site Number :0360003

    Westmead, New South Wales, 2145, Australia

  • Yale University - Site Number:8400007

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.