AI could spot brittle bones from routine chest X-Rays

NCT ID NCT07421713

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an artificial intelligence software called Osteo Signal that analyzes chest X-rays to detect signs of osteoporosis or osteopenia in adults aged 50 and older. Researchers will compare the AI's accuracy against the standard DXA bone density scan using data from 595 people who already had both exams. If it works, this could make osteoporosis screening faster and more accessible without extra tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Osteo Signal (AI software)
What this could lead to
If successful, this could provide a quick, low-cost way to screen for osteoporosis using routine chest X-rays, without extra radiation or visits.
What could go wrong
This is a retrospective study using existing data, not a real-world test. The AI may not work as well in different hospitals or populations, and it only screens for risk, not a diagnosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic osteoporosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Barts Health NHS Trust

    RECRUITING

    London, E1 4DG, United Kingdom

    Contact

  • Erasmus University Medical Center Rotterdam,

    NOT_YET_RECRUITING

    Rotterdam, 3015 GD, Netherlands

    Contact

  • Mid and South Essex NHS Foundation Trust

    NOT_YET_RECRUITING

    Westcliff-on-Sea, Essex, SS0 0RY, United Kingdom

    Contact

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