New talk therapy aims to calm End-of-Life fears in advanced cancer patients
NCT ID NCT07312760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new short-term psychotherapy called ORPHYS, designed to help people with advanced cancer who feel hopeless, lonely, or fearful about the future. 160 patients will be randomly assigned to either ORPHYS or standard psychological support. The goal is to see if ORPHYS reduces demoralization and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
short-term psychodynamic psychotherapy (ORPHYS)
What this could lead to
If it works, this could provide a new way to help advanced cancer patients cope with fear, hopelessness, and loneliness at the end of life.
What could go wrong
This is a relatively small, early-stage trial with 160 participants. The therapy may not prove more effective than standard support, and results may not apply to all cancer patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clinical Institute for Psychosomatic Medicine and Psychotherapy, University Medical Center Düsseldorf
RECRUITINGDüsseldorf, 40225, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Psychosomatics, Psychotherapy and Psychooncology, Medicine II, University of Würzburg
RECRUITINGWürzburg, 97080, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Medical Center Hamburg-Eppendorf
RECRUITINGHamburg, 20246, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••