New talk therapy aims to calm End-of-Life fears in advanced cancer patients

NCT ID NCT07312760

Recruiting now Symptom relief Sponsor: Universitätsklinikum Hamburg-Eppendorf Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new short-term psychotherapy called ORPHYS, designed to help people with advanced cancer who feel hopeless, lonely, or fearful about the future. 160 patients will be randomly assigned to either ORPHYS or standard psychological support. The goal is to see if ORPHYS reduces demoralization and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: short-term psychodynamic psychotherapy (ORPHYS)
What this could lead to: If it works, this could provide a new way to help advanced cancer patients cope with fear, hopelessness, and loneliness at the end of life.
What could go wrong: This is a relatively small, early-stage trial with 160 participants. The therapy may not prove more effective than standard support, and results may not apply to all cancer patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer Death hypertrophic pyloric stenosis neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED CANCER, VARIOUS, NOS

Contacts and locations

Locations

Clinical Institute for Psychosomatic Medicine and Psychotherapy, University Medical Center Düsseldorf
RECRUITING

Düsseldorf, 40225, Germany
Psychosomatics, Psychotherapy and Psychooncology, Medicine II, University of Würzburg
RECRUITING

Würzburg, 97080, Germany
University Medical Center Hamburg-Eppendorf
RECRUITING

Hamburg, 20246, Germany

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