Nasal swab may predict who benefits from cystic fibrosis drug

NCT ID NCT03894657

First seen Jan 11, 2026 · Last updated Apr 28, 2026 · Updated 18 times

Summary

This study looked at whether a test using cells from the nose can predict how well the drug Orkambi works for people with cystic fibrosis. Researchers collected nasal cells from 91 participants before treatment and measured how the drug improved cell function. They then compared these lab results to actual breathing improvements after 24 weeks of taking Orkambi. The goal is to develop a personalized way to identify which patients will benefit most from the therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CYSTIC FIBROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, Île-de-France Region, 75015, France

Conditions

Explore the condition pages connected to this study.