New daily pill aims to tackle both high blood pressure and excess weight
NCT ID NCT06948435
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 31 times
Summary
This phase 3 trial tests a once-daily medication called orforglipron in about 487 adults who have both high blood pressure and obesity or overweight. The study measures how well the drug lowers blood pressure and body weight compared to a placebo. Participants take the pill daily and are monitored for safety and effectiveness over time.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AHEPA University General Hospital of Thessaloniki
Thessaloniki, 546 36, Greece
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Advanced Research Institute
Ogden, Utah, 84405, United States
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Advanced Research Institute - Tigard
Tigard, Oregon, 97223, United States
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All India Institute of Medical Sciences
Bhubaneswar, 751019, India
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AmBeNet GmbH
Leipzig, 04107, Germany
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Angiocentrum Komorany
Prague, 143 00, Czechia
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Arcturus Healthcare , PLC, Troy Internal Medicine Research Division
Troy, Michigan, 48098, United States
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Ascension Saint Agnes Heart Care
Baltimore, Maryland, 21229, United States
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Ashirwad Hospital and Research Centre
Ulhasnagar, 421004, India
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Athens Medical Center - Psychikon branch
Athens, 115 25, Greece
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Balsam Medica
Warsaw, 01-249, Poland
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Beijing Pinggu District Hospital
Beijing, 101200, China
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CCR Ostrava s.r.o
Ostrava, 702 00, Czechia
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CEMEDIC
Buenos Aires, C1407GTN, Argentina
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CHUAC-Complejo Hospitalario Universitario A Coruña
A Coruña, 15001, Spain
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CIPREC
Buenos Aires, C1061AAS, Argentina
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CIPREC
Buenos Aires, C1119ACN, Argentina
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CTC Hodonin s.r.o.
Hodonín, 695 01, Czechia
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Care Access - Brandon
Brandon, Florida, 33510, United States
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Care Access - Mauldin
Mauldin, South Carolina, 29662, United States
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Carient Heart & Vascular - Manassas
Manassas, Virginia, 20109, United States
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Centro de Investigaciones Clínicas Baigorria
Granadero Baigorria, 2152, Argentina
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Centrum Medyczne "Hipokrates" S.C. Elżbieta I Grzegorz Grześk
Bydgoszcz, 85-092, Poland
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Changde First People's Hospital
Changde, 415000, China
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Chase Medical Research, LLC
Waterbury, Connecticut, 06708, United States
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China-Japan Union Hospital
Changchun, 130033, China
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Clinoxus
Prague, 140 00, Czechia
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Clínica nuevas Tecnologías en Diabetes y Endocrinología (NTDE)
Seville, 41003, Spain
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Complejo Asistencial Universitario de León - Hospital de León
León, 24071, Spain
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Dallas Heart and Vascular Consultants, PA
Duncanville, Texas, 75137, United States
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Diahelp s.r.o
Pardubice V, 530 02, Czechia
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Dorado Medical Complex
Dorado, 00646, Puerto Rico
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EAP Osona Sud - Alt Congost S.L.P
Centelles, 08540, Spain
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EAP Sardenya
Barcelona, 08025, Spain
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East-West Medical Research Institute
Honolulu, Hawaii, 96814, United States
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Eastside Research Associates
Redmond, Washington, 98052, United States
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Elite Clinical Studies, LLC
Phoenix, Arizona, 85018, United States
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Excel Clinical Research, LLC
Las Vegas, Nevada, 89109, United States
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Excel Medical Clinical Trials
Boca Raton, Florida, 33434, United States
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Familienmedizinisches Zentrum Radowsky
Leipzig, 04179, Germany
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Fukuwa Clinic
Chūōku, 104-0031, Japan
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FutureMeds GmbH
Berlin, 10629, Germany
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G. Gennimatas General Hospital of Thessaloniki
Thessaloniki, 546 35, Greece
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G.B. Pant Institute of Postgraduate Medical Education & Research
New Delhi, 110002, India
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General Hospital of Athens "G. Gennimatas"
Athens, 11527, Greece
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Hausärztlich-Kardiologisches MVZ am Felsenkeller GmbH/Zentrum für klinische Studien
Dresden, 01277, Germany
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Health Research of Hampton Roads, Inc.
Newport News, Virginia, 23606, United States
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Hospital Quiron Infanta Luisa
Seville, 41010, Spain
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Hospital San Rafael - La Coruña
A Coruña, 15006, Spain
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INECO Neurociencias Oroño
Rosario, 2000, Argentina
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IRMED
Piotrkow Trybunalski, 97-300, Poland
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Instituto Médico Especializado (IME)
Buenos Aires, 1405, Argentina
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Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Medica
Rosario, 2000, Argentina
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Instituto de Investigaciones Clínicas Córdoba
Córdoba, 5000, Argentina
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Jinan Central Hospital
Jinan, 250013, China
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Life Care Hospital and Research Centre
Bangalore, 560092, India
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Lishui Central Hospital
Lishui, China
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Lucida Clinical Trials
New Bedford, Massachusetts, 02740, United States
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MUDr. Sarka Drinkova
Ledeč nad Sázavou, 584 01, Czechia
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Medical Corporation Yuga Tsuruma Kaneshiro Diabetes Clinic
Yamato-shi, 242-0004, Japan
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Medizentrum Essen Borbeck
Essen, 45355, Germany
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Mikannohana Clinic, Diabetes, Endocrinology and Metabolism
Matsuyama, 7900034, Japan
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NZOZ Centrum Medyczne KERmed
Bydgoszcz, 85-231, Poland
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NZOZ Regionalna Poradnia Diabetologiczna
Wroclaw, 50-127, Poland
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National Clinical Research, Inc
Richmond, Virginia, 23294, United States
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North Hills Family Medicine/North Hills Medical Research
North Richland Hills, Texas, 76180, United States
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Northeast Research Institute - Downtown Office
Jacksonville, Florida, 32204, United States
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Ordinace Rihackovi, s.r.o.
Brno, 641 00, Czechia
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Palm Research Center Sunset
Las Vegas, Nevada, 89148, United States
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Papageorgiou General Hospital of Thessaloniki
Thessaloniki, 56403, Greece
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Peace River Cardiovascular Center
Port Charlotte, Florida, 33952, United States
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Praglandia s.r.o
Prague, 150 00, Czechia
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PriMED Clinical Research
Dayton, Ohio, 45429, United States
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Private Practice - Dr. Robert Witek
Tarnów, 33-100, Poland
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Puerto Rico Medical Research
Ponce, 00717, Puerto Rico
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RED-Institut GmbH
Oldenburg, 23758, Germany
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Remington-Davis, Inc
Columbus, Ohio, 43215, United States
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Rochester Clinical Research, LLC
Rochester, New York, 14609, United States
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Ruijin Hospital Shanghai Jiaotong University School of Medicine
Shanghai, 200001, China
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Santa Maria de la Salud Centro Medico
San Isidro, 1642, Argentina
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Shaanxi provincial people's hospital
Xi'an, 710068, China
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Sichuan Provincial People's Hospital
Chengdu, 610072, China
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Siping Central People's Hospital
Siping, 136000, China
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StudyMetrix Research
City of Saint Peters, Missouri, 63303, United States
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Takai Internal Medicine Clinic
Kamakura-shi, 247-0056, Japan
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Texas Institute of Cardiology, PA
McKinney, Texas, 75071, United States
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The First Affiliated Hospital of Henan University of Science &Technology
Luoyang Shi, 471003, China
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The Second Affiliated Hospital of Chongqing Medical University - Yuzhong Campus
Chongqing, 400010, China
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Tokyo-Eki Center-building Clinic
Chūōku, 103-0027, Japan
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Top Moravia Health
Brno, 61500, Czechia
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Universitaetsklinikum Carl Gustav Carus Dresden
Dresden, 01307, Germany
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University Hospital of Ioannina
Ioannina, 45500, Greece
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Uniwersytecki Szpital Kliniczny w Białymstoku
Bialystok, 15-276, Poland
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Valley Clinical Trials, Inc.
Covina, California, 91723, United States
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Valley Clinical Trials, Inc.
Northridge, California, 91325, United States
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Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu
Przemyśl, 37-700, Poland
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Wuxi People's Hospital
Wuxi, 214023, China
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Zentrum fur klinische Forschung - Köln
Cologne, 51069, Germany
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Zentrum für klinische Studien Bad Homburg
Bad Homburg, 61348, Germany
Conditions
Explore the condition pages connected to this study.