Promising new combo for rare lymphoma aims to reduce radiation side effects

NCT ID NCT06583837

First seen Mar 10, 2026 · Last updated May 17, 2026 · Updated 10 times

Summary

This study tests a new approach for people with early-stage MALT lymphoma, a slow-growing cancer of the lymph nodes. Participants first take a targeted drug called orelabrutinib, and then receive an ultra-low dose of radiation (4Gy) only if needed based on their response. The goal is to control the disease effectively while minimizing long-term side effects. About 50 adults with stage I or II MALT lymphoma will take part.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

Conditions

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