Smart cell transplant aims to cure blood cancers with fewer side effects
NCT ID NCT05316701
Summary
This trial is comparing a new, engineered cell transplant called Orca-T against the standard transplant for people with advanced blood cancers like leukemia. The goal is to see if Orca-T can better control the cancer while reducing a serious complication called graft-versus-host disease. About 187 participants will be followed for two years to measure survival and side effects.
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Contacts and locations
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Locations
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City of Hope
Duarte, California, 91010, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Colorado Blood Cancer Institute
Denver, Colorado, 80218, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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OU Health Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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Oregon Health & Sciences University - Knight Cancer Institute
Portland, Oregon, 97239, United States
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Ronald Reagan UCLA Medical Center
Los Angeles, California, 90095, United States
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Sarah Cannon Research Institute
Nashville, Tennessee, 37239, United States
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Stanford Health Care
Stanford, California, 94305, United States
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UC Davis
Sacramento, California, 95817, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Miami Hospital and Clinics - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of Michigan Health System - Michigan Medicine
Ann Arbor, Michigan, 48109, United States
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University of Utah
Salt Lake City, Utah, 84112, United States
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Vanderbilt University
Nashville, Tennessee, 37232, United States
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Weill Cornell Medicine - New York-Presbyterian Hospital
New York, New York, 10021, United States
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Winship Cancer Institute - Emory University
Atlanta, Georgia, 30322, United States
Conditions
Explore the condition pages connected to this study.