New pill tested for Tough-to-Treat blood cancers

NCT ID NCT03740529

Summary

This study tested a new oral medication called pirtobrutinib for people with chronic lymphocytic leukemia or other B-cell lymphomas that had stopped responding to standard treatments. The main goals were to find a safe and effective dose and to see if the drug could shrink tumors. Over 800 patients participated to help determine if this drug could be a new option for controlling these cancers.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu

    Nantes, 44093, France

  • Churchill Hospital

    Oxford, OX3 7LJ, United Kingdom

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Derriford Hospital

    Plymouth, Pl6 8DH, United Kingdom

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Durham VA Medical Center

    Durham, North Carolina, 27705, United States

  • Emory Clinic

    Atlanta, Georgia, 30322, United States

  • Flinders Medical Centre

    Bedford Park, South Australia, 5042, Australia

  • Florida Cancer Specialists

    Sarasota, Florida, 34232, United States

  • Florida Cancer Specialists ORLANDO/DDU

    Lake Mary, Florida, 32746, United States

  • Hokkaido University Hospital

    Sapporo, Hokkaido, 060-8648, Japan

  • IRCCS - AOU di Bologna

    Bologna, 40138, Italy

  • IRCCS Ospedale San Raffaele

    Milan, 20132, Italy

  • Instytut Hermatologii I Transfuzjologii

    Warsaw, Poland

  • Karolinska Institutet

    Solna, AB, 171 65, Sweden

  • Kindai University Hospital

    Osakasayama-Shi, 589-8511, Japan

  • Kochi Medical School Hospital

    Nankoku, Kochi, 783-8505, Japan

  • Kyoto Furitsu Medical University Hospital

    Kyoto, 602-8566, Japan

  • Linear Clinical Research

    Nedlands, Western Australia, 6009, Australia

  • Mary Crowley Cancer Research Center

    Dallas, Texas, 75230, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905-0002, United States

  • Mayo Clinic of Scottsdale

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic-Jacksonville

    Jacksonville, Florida, 32224, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Nagoya Medical Center

    Nagoya, Aichi-ken, 460-0001, Japan

  • National Cancer Center Hospital

    Chuo Ku, Tokyo, 104-0045, Japan

  • National Hospital Organization Kyushu Cancer Center

    Fukuoka, 811-1395, Japan

  • Northwell Health

    New Hyde Park, New York, 11042, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ohio State University Hospital

    Columbus, Ohio, 43210, United States

  • Okayama University Hospital

    Okayama, 700-8558, Japan

  • Ospedale Regionale Bellinzona e Valli

    Bellinzona, Canton Ticino, 6500, Switzerland

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Pratia MCM Krakow

    Krakow, 30-510, Poland

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Samsung Medical Center

    Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea

  • Sarah Cannon Research Institute SCRI

    Nashville, Tennessee, 37203, United States

  • Scripps Coastal Medical Center

    San Diego, California, 92103, United States

  • Seattle Cancer Care Alliance

    Seattle, Washington, 98195, United States

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Smilow Cancer Hospital at Yale-New Haven

    New Haven, Connecticut, 06510, United States

  • St James's University Hospital

    Leeds, LS9 7TF, United Kingdom

  • Swedish Medical Center

    Seattle, Washington, 98104, United States

  • Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • Tohoku University Hospital

    Sendai, Miyagi, 980-8574, Japan

  • Tokai University Hospital- Isehara Campus

    Isehara, Kanagawa, 259-1193, Japan

  • University of California San Francisco, Medical Center at Paranassus

    San Francisco, California, 94117, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68105, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania Hospital

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Utah Cancer Specialists

    Salt Lake City, Utah, 84106, United States

Conditions

Explore the condition pages connected to this study.