New oral drug combo tested to keep Kids' leukemia at bay after transplant

NCT ID NCT07012044

Summary

This early-stage study aims to find a safe dose and understand the side effects of an oral drug combination called ASTX727, given with a white blood cell booster (filgrastim), in children with high-risk acute myeloid leukemia (AML). The treatment is given as 'maintenance therapy' after a stem cell transplant, with the goal of preventing the cancer from returning. The study will enroll up to 47 children and young adults up to age 21 who are in remission after their transplant.

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