Could a common anesthetic replace opioids for ER pain?
NCT ID NCT07670507
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study will test whether oral ketamine can control pain as well as oxycodone in emergency department patients who need extra pain medication. Sixty adults with certain types of pain will be randomly assigned to receive either drug. Researchers will measure changes in pain scores and whether patients need additional opioids within 24 hours, with follow-up at 1 and 3 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oral ketamine
What this could lead to
If it works, this could offer a non-opioid option for managing pain in the emergency department, potentially reducing reliance on opioids.
What could go wrong
This is a small pilot study with only 60 participants, so results may not apply broadly. It's also early-stage, and the effectiveness or side effects of oral ketamine are not yet well understood in this setting.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Albany Medical Center Emergency Department
Albany, New York, 12208, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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