New pill could tame tough eczema without creams

NCT ID NCT06775860

Recruiting now Disease control Sponsor: Beijing InnoCare Pharma Tech Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 3 trial tests an oral drug called ICP-332 for people with moderate to severe atopic dermatitis (eczema) who haven't gotten enough relief from topical treatments. About 552 adults will receive either the drug or a placebo pill for several weeks. Researchers will measure how many achieve at least a 75% improvement in eczema severity and clear skin scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ICP-332 tablets
What this could lead to: If it works, this could provide a new oral treatment option for people with moderate to severe atopic dermatitis who haven't responded well to topical creams.
What could go wrong: This is still an experimental drug. Even in Phase 3, it may not prove more effective than placebo, and side effects are possible. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Affiliated Hospital of Chengde Medical University
RECRUITING

Chengde, Hebei, 067000, China
Affiliated Hospital of Hebei University of Engineering
RECRUITING

Handan, Hebei, 056002, China
Affiliated Hospital of Jiujiang University
RECRUITING

Jiujiang, Jiangxi, 332000, China
Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine
RECRUITING

Tianjin, Tianjin Municipality, 300120, China
Beijing Tongren Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100730, China
Beijing Tsinghua Changgung Hospital
RECRUITING

Beijing, Beijing Municipality, 102218, China
Capital Medical University Affiliated Beijing Chaoyang Hospital
RECRUITING

Beijing, Beijing Municipality, 100020, China
Capital Medical University Affiliated Beijing Friendship Hospital
RECRUITING

Beijing, Beijing Municipality, 100050, China
Central South University Xiangya Hospital
RECRUITING

Changsha, Hunan, 410008, China
Changzhou First People's Hospital
RECRUITING

Changzhou, Jiangsu, 213003, China
Chengdu Second People's Hospital
RECRUITING

Chengdu, Sichuan, 610017, China
Chongqing Traditional Chinese Medicine Hospital
RECRUITING

Chongqing, Chongqing Municipality, 400021, China
Dermatology Hospital of Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510091, China
General Hospital of Tianjin Medical University
RECRUITING

Tianjin, Tianjin Municipality, 300052, China
Hangzhou First People's Hospital
RECRUITING

Hangzhou, Zhejiang, 310006, China
Henan Provincial People's Hospital
RECRUITING

Zhengzhou, Henan, 450003, China
Jiangxi Provincial Dermatology Hospital
RECRUITING

Nanchang, Jiangxi, 330001, China
Jingzhou Central Hospital
RECRUITING

Jingzhou, Hubei, 434020, China
Jining First People's Hospital
RECRUITING

Jining, Shandong, 272011, China
Liuzhou People's Hospital
RECRUITING

Liuzhou, Guangxi, 545006, China
Nanfang Hospital, Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510515, China
Peking University First Hospital
RECRUITING

Beijing, Beijing Municipality, 100034, China
Peking University Third Hospital
RECRUITING

Beijing, Beijing Municipality, 100191, China
Qilu Hospital of Shandong University
RECRUITING

Jinan, Shandong, 250012, China
Sanmenxia Central Hospital
RECRUITING

Sanmenxia, Henan, 472000, China
Second Affiliated Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050000, China
Shaanxi Provincial People's Hospital
RECRUITING

Xi'an, Shaanxi, 710068, China
Shandong Provincial Dermatosis Hospital
RECRUITING

Jinan, Shandong, 250022, China
Shanghai First People's Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200080, China
Shanghai Skin Disease Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200443, China
Shanghai Tenth People's Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200072, China
Shenyang Hospital of Integrated Traditional Chinese and Western Medicine （Shenyang Seventh People's Hospital）
RECRUITING

Shenyang, Liaoning, 110001, China
Shenzhen Second People's Hospital
RECRUITING

Shenzhen, Guangdong, 518035, China
Sichuan Provincial People's Hospital
RECRUITING

Chengdu, Sichuan, 610072, China
Sir Run Run Hospital, Nanjing Medical University
RECRUITING

Nanjing, Jiangsu, 211166, China
The Affiliated Hospital of Inner Mongolia Medical University
RECRUITING

Hohhot, Inner Mongolia, 010050, China
The Affiliated Hospital of Qingdao University
RECRUITING

Qingdao, Shandong, 266003, China
The Affiliated Union Hospital of Fujian Medical University
RECRUITING

Fuzhou, Fujian, 350001, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, 230022, China
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, 400016, China
The First Affiliated Hospital of Fujian Medical University
RECRUITING

Fuzhou, Fujian, 350005, China
The First Affiliated Hospital of Gannan Medical University
RECRUITING

Ganzhou, Jiangxi, 341000, China
The First Affiliated Hospital of Kunming Medical University
RECRUITING

Kunming, Yunnan, 650032, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330006, China
The First Affiliated Hospital of Ningbo University
RECRUITING

Ningbo, Zhejiang, 315010, China
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, Zhejiang, 325000, China
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, Shaanxi, 710061, China
The First Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130021, China
The Fourth Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Yiwu, Zhejiang, 322000, China
The Second Affiliated Hospital of Henan University of Science and Technology
RECRUITING

Luoyang, Henan, 471000, China
The Second Affiliated Hospital of Wannan Medical College
RECRUITING

Wuhu, Anhui, 241000, China
The Second Affiliated Hospital of Xiamen Medical College
RECRUITING

Xiamen, Fujian, 361021, China
The Second Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310009, China
The Second Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410011, China
The Third People's Hospital of Hangzhou
RECRUITING

Hangzhou, Zhejiang, 310009, China
Wuhan Central Hospital
RECRUITING

Wuhan, Hubei, 430014, China
Wuhan Hospital of Traditional Chinese and Western Medicine (Wuhan No.1 Hospital)
RECRUITING

Wuhan, Hubei, 430022, China
Yancheng First People's Hospital
RECRUITING

Yancheng, Jiangsu, 224001, China
Yuebei People's Hospital
RECRUITING

Shaoguan, Guangdong, 512026, China
Yuncheng Central Hospital
RECRUITING

Yuncheng, Shanxi, 440000, China
Zhongshan University Sun Yat-sen Memorial Hospital
RECRUITING

Guangzhou, Guangdong, 510120, China
Zhongyi Northeast International Hospital Co., Ltd.
RECRUITING

Shenyang, Liaoning, 110179, China

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