New daily pill could help control blood sugar in type 2 diabetes

NCT ID NCT05971940

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen May 06, 2026 · Last updated May 06, 2026

Summary

This study tested a once-daily oral medication called orforglipron in 559 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. Participants received either the study drug or a placebo for about 54 weeks. The main goal was to see if the drug safely lowers blood sugar levels (HbA1c) compared to placebo.

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Contacts and locations

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Locations

Abe Clinic

Ōita, 870-0039, Japan
Advance Medical Research Center

San Juan, 00926, Puerto Rico
Affiliated Hospital of Jiangsu University

Zhenjiang, Jiangsu, 212000, China
All India Institute of Medical Sciences (AIIMS) - Nagpur

Nagpur, Maharashtra, 441108, India
Alliance for Multispecialty Research, LLC

New Orleans, Louisiana, 70119, United States
Alliance for Multispecialty Research, LLC

Norman, Oklahoma, 73069, United States
American Health Network of Indiana, LLC - Muncie

Muncie, Indiana, 47304, United States
Amir A Hassan, MD, PA

Houston, Texas, 77089, United States
Ark Clinical Research

Long Beach, California, 90815, United States
BSES MG Hospital

Mumbai, Maharashtra, 400058, India
Beijing Hospital

Beijing, Beijing Municipality, 100730, China
Beijing Pinggu District Hospital

Beijing, Beijing Municipality, 101200, China
Billings Clinic

Billings, Montana, 59101, United States
Burke Internal Medicine and Research

Burke, Virginia, 22015, United States
Central New York Clinical Research

Manlius, New York, 13104, United States
Centricity Research Dublin Multispecialty

Dublin, Ohio, 43016, United States
Centro de Investigacion Medica Integral

Guadalajara, Jalisco, 44160, Mexico
Centro de Investigacion Medica de Occidente, S.C.

Zapopan, Jalisco, 44260, Mexico
Clinical Research Atlanta

Stockbridge, Georgia, 30281, United States
Connecticut Clinical Research - Cromwell

Cromwell, Connecticut, 06416, United States
Ellipsis Research Group - Brooklyn - 7th Street

Brooklyn, New York, 11215, United States
Endocrine Ips, Pllc

Houston, Texas, 77079, United States
Epic Medical Research - Surprise

Surprise, Arizona, 85378, United States
FAICIC S. de R.L. de C.V.

Veracruz, 91900, Mexico
Family First Medical Center

Idaho Falls, Idaho, 83404, United States
Fukuwa Clinic

Chuo-ku, Tokyo, 104-0031, Japan
GMERS Medical College and General Hospital

Vadodara, Gujarat, 390021, India
Global Health Research Center, Inc.

Miami Lakes, Florida, 33016, United States
Grant Medical Foundation - Ruby Hall Clinic

Pune, Maharashtra, 411001, India
Hasegawa Medical Clinic

Chitose, Hokkaido, 066-0032, Japan
Hayashi Diabetes Internal Medicine Clinic

Chigasaki, Kanagawa, 253-0044, Japan
Heishinkai Medical Group ToCROM Clinic

Shinjuku-ku, Tokyo, 160-0008, Japan
Hillcrest Medical Research

DeLand, Florida, 32720, United States
Huizhou Municipal Central Hospital

Huizhou, Guangdong, 516001, China
Infinity Clinical Research - Norco

Norco, California, 92860, United States
Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital

Kolkata, West Bengal, 700020, India
Instituto Veracruzano en Investigación Clínica S.C.

Veracruz, 91851, Mexico
Investigacion En Salud Y Metabolismo S.C / Nutricion Clinica / Unidad de Base de Datos

Chihuahua City, 31110, Mexico
Invictus Clinical Research Group

Coconut Creek, Florida, 33073, United States
Iwamoto Clinic

Zentsujichó, Kagawa-ken, 765-0071, Japan
Jinan Central Hospital

Jinan, Shandong, 250013, China
Juno Research

Houston, Texas, 77040, United States
K2 Medical Research

Maitland, Florida, 32751, United States
Kumudini Devi Diabetes Research Center

Hyderabad, Telangana, 500072, India
Lucas Research - New Bern

New Bern, North Carolina, 28562, United States
Luhe Hospital

Beijing, Beijing Municipality, 100000, China
M S Ramaiah Medical College and Hospitals

Bangalore, Karnataka, 560054, India
MDFirst Research, LLC

Lancaster, South Carolina, 29720, United States
Madras Diabetes Research Foundation

Chennai, Tamil Nadu, 600086, India
Medical Corporation Heishinkai OCROM Clinic

Suita-shi, Osaka, 565-0853, Japan
Medical Corporation Yuga Tsuruma Kaneshiro Diabetes Clinic

Yamato-shi, Kanagawa, 242-0004, Japan
Medstar Speciality Hospital

Bangalore, Karnataka, 560092, India
MinamiAkatsukaClinic

Mito, Ibaraki, 311-4153, Japan
Monroe Biomedical Research

Monroe, North Carolina, 28112, United States
Morinaga Ueno Clinic

Kumamoto, 860-0863, Japan
Nanjing First Hospital

Nanjing, Jiangsu, 210006, China
Nanyang First People's Hospital

Nanyang, Henan, 473001, China
Neighborhood Healthcare Institute of Health

Escondido, California, 92025, United States
Norcal Endocrinology & Internal Medicine

San Ramon, California, 94583, United States
PanAmerican Clinical Research - Querétaro - Avenida Antea

Querétaro, 76100, Mexico
Preferred Primary Care Physicians

Uniontown, Pennsylvania, 15401, United States
Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair

Pittsburgh, Pennsylvania, 15243, United States
Pudong New Area People's Hospital Shanghai

Shanghai, Shanghai Municipality, 201200, China
Puerto Rico Health Institute

Dorado, 00646, Puerto Rico
Quality of Life Medical & Research Center

Tucson, Arizona, 85712, United States
Revival Research Institute

Dearborn, Michigan, 48126, United States
Rophe Adult and Pediatric Medicine/SKYCRNG

Union City, Georgia, 30291, United States
Salud Cardiovascular

Guadalajara, Jalisco, 44860, Mexico
Shunde Hospital of Southern Medical Univesity

Foshan, Guangdong, 528399, China
Steel Memorial Yahata Hospital

Kitakyushu, Fukuoka, 805-8508, Japan
Syed Research Consultants Llc

Sheffield, Alabama, 35660, United States
Tekton Research - Wichita

Wichita, Kansas, 67218, United States
The Corvallis Clinic, P.C.

Corvallis, Oregon, 97330, United States
The Fourth Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, 150001, China
The Institute of Medical Science, Asahi Life Foundation

Chuo-ku, Tokyo, 103-0002, Japan
The Jackson Clinic

Jackson, Tennessee, 38305, United States
The Research Center of The Upstate

Greenville, South Carolina, 29607, United States
The Second Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, 210011, China
The Second Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, 450014, China
Tokuyama Clinic

Mihama-ku,Chiba City, Chiba, 261-0004, Japan
Tokyo-Eki Center-building Clinic

Chuo-ku, Tokyo, 103-0027, Japan
Unidad de Investigaci�n Cl�nica Cardiometabolica de Occidente

Guadalajara, Jalisco, 44150, Mexico
University Clinical Investigators, Inc.

Tustin, California, 92780, United States
Velocity Clinical Research, Dallas

Dallas, Texas, 75230, United States
Velocity Clinical Research, Huntington Park

Huntington Park, California, 90255, United States
Velocity Clinical Research, Westlake

Los Angeles, California, 90057, United States
Wannan Medical College Yijishan Hospital

Wuhu, Anhui, 241001, China
West China Hospital of Sichuan University

Chengdu, Sichuan, 610041, China
West Orange Endocrinology

Ocoee, Florida, 34761, United States

Conditions

Explore the condition pages connected to this study.

TYPE 2 DIABETES