Can a 5-Day steroid course tame COPD Flare-Ups?

NCT ID NCT02330952

Completed Symptom relief Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether taking oral corticosteroids (prednisone) for 5 days can help people with COPD who are having a flare-up. The trial involved 189 adults aged 40 and older who were treated in general practice. Researchers tracked treatment failure, including emergency visits or hospitalizations, over 8 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prednisone (a corticosteroid)
What this could lead to: If successful, this could confirm that a short course of oral steroids is an effective and safe treatment for COPD flare-ups in outpatient settings.
What could go wrong: This is a completed Phase 4 trial with 189 participants, so results are available but may not apply to all COPD patients. Corticosteroids have known side effects like increased infection risk and blood sugar changes.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease lung disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC OBSTRUCTIVE (MESH) PULMONARY DISEASE

Contacts and locations

Locations

Assistance Publique - Hopitaux Paris

Paris, 75014, France

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