Pill-Based leukemia treatment challenges standard IV chemo

NCT ID NCT04817241

Summary

This study is testing whether a combination of pills (ASTX727 and venetoclax) is as safe and effective as standard intravenous chemotherapy for younger adults with a high-risk type of acute myeloid leukemia (AML). The goal is to control the cancer and improve survival. The trial first finds a safe dose, then compares the pill combination to the standard treatment.

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Contacts and locations

Locations

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, 35233, United States

  • University of Virginia Cancer Center

    Charlottesville, Virginia, 22908, United States

  • Vanderbilt University/Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.