Less may be more: prostate cancer surgery trial tests lymph node removal

NCT ID NCT07308990

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether removing fewer lymph nodes during prostate cancer surgery is as safe and effective as removing more. Researchers will compare two groups of 800 men with prostate cancer who are having their prostate removed. One group will have a limited lymph node removal, the other a more extensive one. The goal is to see if the less invasive approach can reduce complications without increasing the risk of cancer spreading.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors know exactly how many lymph nodes to remove during prostate cancer surgery, balancing cancer control with fewer complications.
What could go wrong
This is an early-stage study comparing two surgical approaches, not testing a new drug. Results may not change standard practice immediately, and individual patient factors could affect outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • N.N. Alexandrov National Cancer Centre

    RECRUITING

    Lyasny, Minsk Oblast, 223040, Belarus

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