New MRI technique could better track lung treatment success

NCT ID NCT04855305

First seen Nov 21, 2025 · Last updated Jun 20, 2026 · Updated 30 times

Summary

This study tested a special MRI technique using a harmless gas to see how well it can show changes in the lungs of people with interstitial lung disease. Researchers worked with 46 volunteers to find the best way to use this scan. The goal is to create a standard method that doctors can use to monitor if treatments are working.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperpolarized 129Xe gas

What this could lead to

If successful, this could improve how doctors monitor lung disease treatment using a non-invasive MRI technique.

What could go wrong

This is a small, early-phase study focused on refining imaging methods, not testing a treatment. The technique may not prove reliable enough for widespread use.

Conditions

The condition(s) this trial relates to.

interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.