Monthly shot may help hospitalized patients stick with opioid addiction treatment

NCT ID NCT04345718

First seen Jan 08, 2026 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tested whether a once-monthly injection of extended-release buprenorphine helps hospitalized patients with moderate to severe opioid use disorder stay in treatment better than usual care. Over 300 adults were randomly assigned to receive the shot or standard treatment before leaving the hospital. Researchers checked if patients were still engaged in care 34 days later, and followed up at 90 and 180 days.

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Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02118, United States

  • Hennepin Healthcare Research Institute

    Minneapolis, Minnesota, 55404, United States

  • Johns Hopkins Bayview Medical Center

    Baltimore, Maryland, 21224, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.