Knee surgery study tests Opioid-Free anesthesia to curb addiction risk
NCT ID NCT07211399
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 35 times
Summary
This study looks at whether using no opioids during knee replacement surgery can help prevent patients from becoming dependent on painkillers later. Researchers will compare two groups: one that gets standard opioid anesthesia and one that gets opioid-free anesthesia with other pain medicines. The goal is to see if avoiding opioids during surgery reduces chronic pain and long-term opioid use. The study will enroll 700 adults scheduled for knee replacement.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UPMC Shadyside Hospital
Pittsburgh, Pennsylvania, 15232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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